Recent advances in the neurobiology of alcoholism: the role of adenosine

As the VTA is a major nucleus of dopamine cell bodies, we explicitly assessed changes in connectivity with the VTA induced by depletion of dopamine precursors. Based on the preclinical evidence of a reduction in alcohol consumption via blockade of dopamine D2 receptors, the potential of dopamine D2 antagonists as a pharmacotherapy for alcohol dependence … Read more

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